Every meeting

28 Mar 2021 AFCON Qualifiers · Group stage	Ghana	3–1	Sao Tome and Principe	W
18 Nov 2019 AFCON Qualifiers · Group stage	Sao Tome and Principe	0–1	Ghana	W

This record covers meetings from 18 November 2019 onwards. Earlier games between these teams aren't on the site yet, so the all-time totals may be higher.
W / D / L from Ghana's side. Penalty shootouts count as draws.