Every meeting

14 Jun 2023 AFCON Qualifiers · Group stage	Sao Tome and Principe	0–1	Guinea-Bissau	W
9 Jun 2022 AFCON Qualifiers · Group stage	Guinea-Bissau	5–1	Sao Tome and Principe	W
10 Sep 2019 World Cup Qualifiers (CAF) · 1st Round	Guinea-Bissau	2–1	Sao Tome and Principe	W
4 Sep 2019 World Cup Qualifiers (CAF) · 1st Round	Sao Tome and Principe	0–1	Guinea-Bissau	W

This record covers meetings from 4 September 2019 onwards. Earlier games between these teams aren't on the site yet, so the all-time totals may be higher.
W / D / L from Guinea-Bissau's side. Penalty shootouts count as draws.