Every meeting

16 Nov 2020 AFCON Qualifiers · Group stage	Sao Tome and Principe	2–4	South Africa	L
13 Nov 2020 AFCON Qualifiers · Group stage	South Africa	2–0	Sao Tome and Principe	L

This record covers meetings from 13 November 2020 onwards. Earlier games between these teams aren't on the site yet, so the all-time totals may be higher.
W / D / L from Sao Tome and Principe's side. Penalty shootouts count as draws.